Thick Brain Slices Model the Ischemic Penumbra
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چکیده
منابع مشابه
Thick penumbra in a magnetostatic sunspot model
The conjecture that energy transport in sunspot penumbrae occurs through convection by an interchange of magnetic flux tubes is used in order to construct a magnetostatic model for a deep penumbra which is part of a global sunspot model. The model describes an overall mechanical equilibrium between the three stratifications: of the umbra, the penumbra, and of the solar convection zone, all of t...
متن کاملThe cerebral ischemic penumbra.
When neuronal activity is suppressed by ischemia of sufficient severity, maintained for a long enough period of time, permanent clinical deficit can be accompanied by radiographic signs of cerebral infarction and histological evidence of ischemic damage. Recent work suggests that this is not an all-ornone event. Between the most densely ischemic region and the more normally perfused brain, an i...
متن کاملTargeting the ischemic penumbra.
BACKGROUND In the last 3 decades, and from a therapeutic point of view, the classical concept of ischemic penumbra based on hemodynamic and electrophysiological parameters has loosened up the rigidity of therapeutic windows in acute stroke management. Thirty years later, the ischemic penumbra is an evolved concept that presents more applications. Thus, the ischemic penumbra is a diagnostic targ...
متن کاملImplications of ischemic penumbra for the diagnosis of brain death.
The data reviewed here suggest the possibility that a global reduction of blood supply to the whole brain or solely to the infratentorial structures down to the range of ischemic penumbra for several hours or a few days may lead to misdiagnosis of irreversible brain or brain stem damage in a subset of deeply comatose patients with cephalic areflexia. The following proposals are advanced: 1) the...
متن کاملMRI Measurement of Ischemic Brain Penumbra Using an Inelastic Collision Model
Introduction: Multi-parametric MRI analysis of the ischemic lesions of stroke patients demonstrates inhomogeneities in the degree of ischemic injury and recovery potential [1]. Experimental and clinical studies indicate that the likelihood for progression to infarction in the penumbra of physiologically impaired but potentially salvageable tissue surrounding the central core of focal cerebral i...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 1988
ISSN: 0271-678X,1559-7016
DOI: 10.1038/jcbfm.1988.100